Session Key Points

  • Cholinergic receptors are subdivided into nicotinic and muscarinic receptors: the neuromuscular junction is nicotinic in nature
  • Motor neurones control the activity of muscle fibres; the motor neurone and the muscle fibres it controls is termed the motor unit
  • Action potentials are propagated by saltatory conduction across Nodes of Ranvier
  • Nicotinic receptors consists of five subunits. Each alpha subunit has a single acetylcholine binding region
  • Actin (together with troponin and tropomyosin) makes up the thin filaments in muscles. The thick filaments are made of myosin
  • Muscles contract by a process called excitation-contraction coupling