It is important that you understand the various preparations of adrenaline.
The concentration of adrenaline is commonly expressed as 1 in 1000 or 1 in 10 000.
This notation refers to the weight in grams of drug present in X ml of fluid. For example, the concentration of 1 in 1000 adrenaline is 1 g in 1000 ml or 1 mg/ml.
Adrenaline is very potent, so concentrations in common use are relatively dilute so that the volume part always appears large.
Question: How many μg of adrenaline is present is 0.5 ml of a 1 in 1000 solution?
Question: How many μg of adrenaline is present is 0.5 ml of a 1 in 1000 solution?
Answer: 1 in 1000 of adrenaline is 1 mg/ml; 0.5 ml contains 0.5 mg, which is 500 μg.
This is a very concentrated preparation of adrenaline and should only be used IM.
Question: What is 1 in 10 000 of adrenaline expressed as μg/ml?
Question: How many μg of adrenaline is present is 0.5 ml of a 1 in 1000 solution?
Answer: 1 in 1000 of adrenaline is 1 mg/ml; 0.5 ml contains 0.5 mg, which is 500 μg.
This is a very concentrated preparation of adrenaline and should only be used IM.
Question: What is 1 in 10 000 of adrenaline expressed as μg/ml?
Answer: 1 in 10 000 adrenaline is 1 g per 10 000 ml or more usefully 100 μg/ml. To give 50 μg, you need just 0.5 ml.
This is the preparation that should be used IV.